Based on the distribution of the r-values in these random correlations, P -values were determined, indicating that all correlations are highly significant with P -values of 3.8 × 10 −4 for N2 flanks and 1.2 × 10 −4 for N3 flanks, respectively.
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Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns.
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