Biphasic Dose-Response and Hormetic Effects of Stress Hormone Hydrocortisone on Telomerase-Immortalized Human Bone Marrow Stem Cells In Vitro.

This was followed by a range of HC concentrations (between 2 and 100 μmol/L), where no significant differences between the untreated and HC-treated cells were observed, after which at 125 and 150 μmol/L HC concentrations, a highly significant decline (up to 50% decline) in MTT activities was observed ( Figure 1A ).

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