Impact of co-existence of PMQR genes and QRDR mutations on fluoroquinolones resistance in Enterobacteriaceae strains isolated from community and hospital acquired UTIs.

Detection of PMQR genes ( qnrB and qnrS ) was strongly correlated with FQs resistance levels in resistant isolates with a correlation coefficient equal to 0.8 (r = 0.8) and 0.9 (r = 0.8) respectively which was highly significant ( p value; 0.0001) for both genes as well as qepA gene with a correlation coefficient equal to 0.25 (r = 0.25) which was considered fair but significant ( p value; 0.006).

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