Freezing of Gait can persist after an acute levodopa challenge in Parkinson's disease.

NPJ Parkinsons Dis · 2019 · PMC6874572 · PMID 31799377

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highly significantno p-value reported

Linear mixed models revealed a highly significant association between serum levodopa level and total MDS-UPDRS-III score that was similar across groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.