Linking Tumor Growth Dynamics to Survival in Ipilimumab-Treated Patients With Advanced Melanoma Using Mixture Tumor Growth Dynamic Modeling.

CPT Pharmacometrics Syst Pharmacol · 2019 · PMC6875707 · PMID 31334596

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1 , 7 , 12 However, unlike previously reported analyses of TGD OS, our OS model also included an effect for missing postbaseline TB, which was a highly significant negative predictor of the risk of death ( Figure 3 ; HR, 6.28; 95% CI, 5.00–7.87).

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