Barely Significant
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TLR9 activation cooperates with T cell checkpoint blockade to regress poorly immunogenic melanoma.

J Immunother Cancer · 2019 · PMC6880482 · PMID 31771649

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highly significantno p-value reported
These data demonstrate that highly significant improvements in survival and cure rate for bilateral melanoma can be achieved by using higher potency TLR9 and CTLA-4 blocking / depleting antibodies.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.