A p value of < 0.05 was considered statistically significant whereas a p value of < 0.1 was taken to reflect a trend towards significance.
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Type of preoperative therapy and stage-specific survival after surgery for rectal cancer: a nationwide population-based cohort study.
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The sentences
The observed difference in stage-specific survival between patients treated with CRT (substantial downstaging) and SC-RT (no downstaging) was substantial and highly significant, and the effect was independent of several known possible confounders.