Immunohistological staining of unknown chemokine RANTES/CCL5 expression in jawbone marrow defects-osteoimmunology and disruption of bone remodeling in clinical case studies targeting on predictive preventive personalized medicine.

Clinical cases (group 1) from the jaw area—comparison of X-ray diagnostics, R/C expression, light microscopy, and immunohistochemistry All cases shown in “ Clinical cases (group 1) from the jaw area—comparison of X-ray diagnostics, R/C expression, light microscopy, and immunohistochemistry –“ Summary of results ” share common features along with inconspicuous, two-dimensional X-ray diagnostics: they exhibit a positive diagnosis for FDOJ based on transalveolar ultrasonography (TAU)—a measurement of bone density, where bone density < 150 HU (class 5 HU) indicates highly significant osteolysis—and demonstrated noticeable softening and fatty degenerative changes in medullary morphology.

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