Abnormal lacuno-canalicular network and negative correlation between serum osteocalcin and Cobb angle indicate abnormal osteocyte function in adolescent idiopathic scoliosis.

FASEB J · 2019 · PMC6894095 · PMID 31626573

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a decreasing trendno p-value reported

The negative correlation between curve severity and serum osteocalcin and sclerostin suggests a decreasing trend of osteocyte activity in AIS as the curve progresses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.