Cerebrospinal fluid and plasma biomarker trajectories with increasing amyloid deposition in Alzheimer's disease.

The Aβ40 finding should also be interpreted cautiously since this initial decline was driven by few individuals and the Aβ40 model was barely significant for CSF ( P = 0.02; Appendix Fig S1 ) and was not significant for plasma ( P = 0.37; Appendix Fig S2 ).

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