The XBP gene expression presented a highly significant 45-fold increase in the gene expression in the 4 μM defensin-treated HT29 line and a 15-fold increase for the 15 μM defensin concentration compared to the untreated line.
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Modulation of the activity of certain genes involved in tumor cell metabolism in the presence of the cytotoxic peptides defensin and cathelicidin LL37.
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