Liquid and softgel capsules of l-thyroxine results lower serum thyrotropin levels more than tablet formulations in hypothyroid patients.

However, when the five groups were pooled making possible to compare a large number of TSH determinations, then the liquid formulation-associated TSH levels were barely significantly greater than the capsule counterpart (1.62 ± 0.51 vs 1.77 ± 0.44 mU/L, P = 0.049) ( Table 1 ).

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P values below 0.05 were considered to be statistically significant, while P values between 0.05 and 0.10 were considered to be borderline significant.

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