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Opioid-Related Hospitalization and Its Association With Chronic Diseases: Findings From the National Inpatient Sample, 2011-2015.

Prev Chronic Dis · 2019 · PMC6896831 · PMID 31775008

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an increasing trendno p-value reported
Despite these limitations, our findings show an increasing trend in opioid-related hospitalization among patients with chronic diseases and a high prevalence of opioid-related hospitalization among patients with multiple chronic conditions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.