Barely Significant
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Renal function change after switching tenofovir disoproxil fumarate for tenofovir alafenamide in the HIV-positive patients of a metropolitan sexual health service.

AIDS Res Ther · 2019 · PMC6898922 · PMID 31810490

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highly significantno p-value reported
Although a highly significant trend between lower pre-switch eGFR and eGFR improvement post-switch to TAF was observed, further study will be needed in larger patient groups to better characterize the relationship between baseline eGFR change and the eGFR response in patients switched from TDF to TAF-containing regimens.

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