Properdin: A Novel Target for Neuroprotection in Neonatal Hypoxic-Ischemic Brain Injury.

We observed an overall trend toward reduction of ipsilateral brain tissue volume loss of 13–66% across all 6 forebrain regions in the LPS-treated global properdin deletion group ( Figure 2H ) compared to LPS-treated wild type controls ( Figure 2G ) (main effect, p < 0.05, Kruskal-Wallis test), however the data reached significant values only in cortex and pyriform cortex (Bonferroni correction, p < 0.05).

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