There was a nonsignificant trend toward a lower incidence of HF hospitalizations among patients with an EF between 45% and 49% who were receiving β-blockers (hazard ratio, 0.68 [95% CI, 0.28-1.63]; P = .39).
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Association of β-Blocker Use With Heart Failure Hospitalizations and Cardiovascular Disease Mortality Among Patients With Heart Failure With a Preserved Ejection Fraction: A Secondary Analysis of the TOPCAT Trial.
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