highly significantp<0.001
Results from the Diabetes Control and Complications Trial (DCCT) in the US and Canada for Type 1 DM and the United Kingdom Prospective Diabetes Study (UKPDS) for Type 2 DM demonstrate highly significant reductions (DCCT, p<0.001; UKPDS, p = 0.009) in the incidence and progression of retinopathy in patients randomized to tight blood glucose control (HbA1c <7%).