The combined use of AChEI+memantine has been evaluated in a meta-analysis by Matsunaga et al; the results showed a better outcome of the combined therapy compared to AChEI alone in both behavioral and functional scores, with also a positive trend in cognitive performance ( Matsunaga et al., 2014 ).
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The Use of Antipsychotic Drugs for Treating Behavioral Symptoms in Alzheimer's Disease.
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