Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles.

Multiple regression analyses or multiple ordinal logistic regression analysis did not show significant interaction of ZnO-NPs exposure level and Nrf2 deletion for the above parameters, thus multiple regression model without the interaction was applied for them, although marginally significant interaction is noted for neutrophils ( p = 0.06) as it indicates different effect of ZnO-NP exposure level depending on the genotype.

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