highly significantp < 0.001
The ANOVA results were highly significant for the variability in spike numbers between cells (CV b ; F (29,1420) = 32.04, p < 0.001) and differences in spike numbers between WT and KO for older animals ( F (1,1420) = 209.9, p < 0.001), but across-trial comparisons did not exhibit a significant difference ( F (24,1420) = 0.15, p = 1).Thus, there is an increase in spike variability with lowered spiking precision for adult KO mice compared with juvenile KO mice.