The Italian OBSERVANT Registry reported a trend towards significance for female sex as a protective factor (p=0.05; OR 0.61).[ 39 ] Results are even stronger if focusing on studies in which CoreValve use is dominant, such as the meta-analysis by Zhao et al.[ 11 ] One suggested explanation for the higher incidence of permanent pacemaker implantation in men as compared to women is the use of larger prostheses.
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Sex and Transcatheter Aortic Valve Implantation: Impact of Female Sex on Clinical Outcomes.
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