The long noncoding RNA <i>neuroLNC</i> regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43.

The sole highly significant enriched interactor of neuroLNC is the RNA-binding protein TDP-43, a central player in the pathogenesis of neurodegenerative disorders ( 27 ) such as frontotemporal lobar degeneration (FTLD; also known as frontotemporal dementia) and amyotrophic lateral sclerosis (ALS).

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