Angiotensin II Type I Receptor Antagonism Attenuates Nicotine-Induced Cardiac Remodeling, Dysfunction, and Aggravation of Myocardial Ischemia-Reperfusion Injury in Rats.

Front Pharmacol · 2019 · PMC6920178 · PMID 31920673

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failed to attain significanceP < 0.1so close (0.05 < p ≤ 0.1)

Irbesartan exhibited a tendency to attenuate these changes, compared to nicotine-administered rats, but failed to attain significance (all P < 0.1; Table 2 ).

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