The p -value was highly significant ( P ˂ 0.0001) and the lack-of-fit p -value was larger than 0.05 (0.1562), which indicates that the fitted regression equation was good and capable of explaining and predicting the results.
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Modified Spraying Technique and Response Surface Methodology for the Preparation and Optimization of Propolis Liposomes of Enhanced Anti-Proliferative Activity against Human Melanoma Cell Line A375.
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