Improvement of developmental competence of cloned male pig embryos by short hairpin ribonucleic acid (shRNA) vector-based but not small interfering RNA (siRNA)-mediated RNA interference (RNAi) of Xist expression.

However, the injections of 5 and 10 ng/μl of pU6-shRNA plasmid into cloned male pig embryos resulted in an almost significant (P = 0.07) and significant decrease in Xist transcription level at the blastocyst stage, respectively ( Fig. 5B ).

also in 1,858 other papers