Epigenetic and Transcriptomic Characterization of Pure Adipocyte Fractions From Obese Pigs Identifies Candidate Pathways Controlling Metabolism.

Front Genet · 2019 · PMC6927937 · PMID 31921306

Europe PMC DOI

hedged sentences

0.0050

closest p · 0.1× alpha

0.1000

boldest claim

The sentences

highly significantp < 0.005actually significant

We identified strong and highly significant correlations (r > ±0.6, p < 0.005) between the amount of retroperitoneal fat and the expression of ADIPOQ (r = −0.65, p = 0.003), GRB10 (r = −0.62, p = 0.005), INPPL1 (r = 0.71, p = 0.0006), LEP (r = 0.74, p = 0.0003), OSBPL10 (r = 0.69, p = 0.001), RNF10 (r = 0.70, 0.0009), and SP1 (r = −0.65, p = 0.002).

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almost reached significancep < 0.1so close (0.05 < p ≤ 0.1)

MTOR , SYNE1 , and IDS , which almost reached significance level in the gene expression analysis [ p < 0.1, FC > 1.2, Supplementary Table S3(2) ], also showed significant correlation between methylation levels and gene expression.

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