Heterozygous Ldlr-Deficient Hamster as a Model to Evaluate the Efficacy of PCSK9 Antibody in Hyperlipidemia and Atherosclerosis.

Evolocumab or Ezetimibe Treatment Reduced HFHC Diet-Induced Hyperlipidemia HFHC diet feeding increased plasma TC, TG, LDL-C, and HDL-C levels from day 3 in Ldlr+/− hamsters, the levels gradually increased in the following 12 weeks and then had a decreasing trend ( Figure 2 ).

also in 47,180 other papers