Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1).

Mol Psychiatry · 2021 · PMC6930366 · PMID 31239533

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Discussion This study reports a differential pattern of genome-wide DNA methylation in BA10 of AUD subjects, indicating that the majority of the highly significant differentially methylated CpGs (~61% of 1218 CpGs), including the CpG of NR3C1 1H , were hypermethylated in AUD subjects.

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