The Effect of Berberine on Reproduction and Metabolism in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Control Trials.

Berberine had slightly decreased LH and FSH but did not quite achieve significance (4 RCTs, 262 participants, MD: −0.49, 95% CI: −1.31 to 0.33, I 2 = 0; MD: −0.17, 95% CI: −0.79 to 0.45, I 2 = 82%, respectively) [ 15 , 25 , 31 , 33 ] ( Table 2 ).

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