ORF6 and ORF61 Expressing MVA Vaccines Impair Early but Not Late Latency in Murine Gammaherpesvirus MHV-68 Infection.

At day 17, MVA-ORF6- and MVA-ORF61-pre-immunized mice showed a highly significant reduction in spleen weight ( Figure 5B ) and a decrease in latent virus as quantified by the number of reactivating splenocytes ( Figure 5C ) as compared to the control groups (MVA-F6 or PBS).

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