In addition, IHC of tumour samples revealed an increasing trend of FASN expression in the gemcitabine treatment group, while FASN expression was repressed in the α‐mangostin and gemcitabine combination treatment group.
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α-Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades.
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