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α-Mangostin suppresses the de novo lipogenesis and enhances the chemotherapeutic response to gemcitabine in gallbladder carcinoma cells via targeting the AMPK/SREBP1 cascades.

J Cell Mol Med · 2020 · PMC6933365 · PMID 31762191

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an increasing trendno p-value reported
In addition, IHC of tumour samples revealed an increasing trend of FASN expression in the gemcitabine treatment group, while FASN expression was repressed in the α‐mangostin and gemcitabine combination treatment group.

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