Differential skewing of donor-unrestricted and γδ T cell repertoires in tuberculosis-infected human lungs.

The dominant Vδ gene in the lung was Vδ1, and this difference was highly significant in HIV neg subjects with active TB, who had an increased frequency of Vδ1/Jδ1 rearrangements and a reciprocal reduction in the relative amount of Vδ2/Jδ1 ( Figure 6, C–E ).

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