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Virus-based pharmaceutical production in plants: an opportunity to reduce health problems in Africa.

Virol J · 2019 · PMC6937724 · PMID 31888686

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an increasing trendno p-value reported
Consequently, there has been an increasing trend toward the improvement of the use of plants as bioreactors in recent years.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.