The carbohydrate-insulin model does not explain the impact of varying dietary macronutrients on the body weight and adiposity of mice.

There was a positive relationship between the post-prandial insulin levels and carbohydrate intake, which almost reached significance (linear regression: F 1,33 = 3.701, R 2 = 0.101, p = 0.063) ( Figure 1 A).

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