Opioid free onco-anesthesia: Is it time to convict opioids? A systematic review of literature.

J Anaesthesiol Clin Pharmacol · 2019 · PMC6939563 · PMID 31920226

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an increasing trendno p-value reported

This has led to an iatrogenic addiction[ 2 3 ] 75% heroin users admitted having initially started off with a left-over prescription opioid which later led to addiction[ 2 3 ] Amidst an increasing trend of opioid-related death, closed claims revealed that 88% of opioid-related death (ORD) occurred within 24 postoperative hours due to undetected respiratory depression especially in the obese.

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