Barely Significant
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Pathogenic variants in the DEAH-box RNA helicase DHX37 are a frequent cause of 46,XY gonadal dysgenesis and 46,XY testicular regression syndrome.

Genet Med · 2020 · PMC6944638 · PMID 31337883

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantP value = 5.8 × 10 −10actually significant
Enrichment of rare/novel DHX37 missense variants in 46,XY DSD is highly significant compared with controls ( P value = 5.8 × 10 −10 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.