Development of Prodrugs for PDT-Based Combination Therapy Using a Singlet-Oxygen-Sensitive Linker and Quantitative Systems Pharmacology.

J Clin Med · 2019 · PMC6947033 · PMID 31847080

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noticeably significantno p-value reported

There was a noticeably significant difference in cytotoxicity between CA4 conjugated to the photosensitizer through the singlet-oxygen-sensitive linker and CA4 conjugated through a noncleavable linker ( Table 1 , entry 5a, b).

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