Introduction Predicting release from degradable hydrogel networks is highly significant for a multitude of applications: designing multilayered or multicomponent drug delivery devices; controlling drug or other molecule delivery by pore size, pore size distribution, affinity, or other interactions (Lin and Metters, 2006 ), facilitating nutrient and gas exchange in three-dimensional cell scaffolds for tissue engineering (Leddy et al., 2004 ), controlling solute diffusivity via crowding and confinement to enhance extracellular matrix production by cells to create tissues ex vivo (Chen et al., 2011 ), and many others.
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Predicting Drug Release From Degradable Hydrogels Using Fluorescence Correlation Spectroscopy and Mathematical Modeling.
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