Barely Significant
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The M2 macrophage marker <i>CD206</i>: a novel prognostic indicator for acute myeloid leukemia.

Oncoimmunology · 2020 · PMC6959428 · PMID 32002295

2
hedged sentences
0.0580
closest p · 1.2× alpha
0.0580
boldest claim

The sentences

a trend toward significanceP = .058so close (0.05 < p ≤ 0.1)
Remarkably, we found that 3 of the 4 genes – CD68, CD163 , and CD206 – whose increased expression levels were significantly associated with worse OS ( P = .009, P = .023, and P = .001, respectively; Supplementary Figure S11A); though for EFS only CD206 showed a trend toward significance ( P = .058, Supplementary Figure S11B).

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highly significantno p-value reported
Notably, the predictive power of CD206 was especially pronounced in CN-AML patients; it exhibited a highly significant association with survival in almost all CN-AML cohorts (Supplementary Figure S16), with an overall p -value of 2.44 × 10 −11 for OS and 1.66 × 10 −7 for EFS ( Figure 7d ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.