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Colistin Combined With Tigecycline: A Promising Alternative Strategy to Combat <i>Escherichia coli</i> Harboring <i>bla</i> <sub>NDM-</sub> <sub>5</sub> and <i>mcr-1</i>.

Front Microbiol · 2019 · PMC6960404 · PMID 31969868

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highly significantno p-value reported
coli 1320 that carried both bla NDM– 5 and mcr-1 displayed a highly significant synergistic response to this combination across the range of drug concentrations tested, with a clear peak at 0.5 mg/L tigecycline and 1 or 2 mg/L colistin ( Figure 2A ).

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