Barely Significant
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Influence of Alcohol on Phosphodiesterase 5 inhibitors Use in Middle- to Old-Aged Men: A Comparative Study of Adverse Events.

Sex Med · 2019 · PMC6963111 · PMID 31444051

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might be significantno p-value reported
Although the rate of cardiac symptoms in the cohort was low, we believe the risk of alcohol consumption with PDE-5 inhibitors might be significant enough to induce coronary disease or systemic hemodynamic instability.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.