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Trends in Antimicrobial Resistance Patterns in Neisseria Gonorrhoeae in Australia and New Zealand: A Meta-analysis and Systematic Review.

Antibiotics (Basel) · 2019 · PMC6963718 · PMID 31652729

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an increasing trendno p-value reported
There is a need to strengthen the monitoring of the dual therapy regime in Australia in light of an increasing trend in reduced susceptibility to ceftriaxone and the emergence of highly resistant strains to azithromycin.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.