4 , 68 The upregulation of AMACR in prostate cancer is highly significant to the extent that it is used as a bona fide biomarker for early detection and diagnosis of prostate cancer. 68 Furthermore, it also suggests that β-oxidation, particularly of branched-chain FAs, is the main bioenergetic pathway for obtaining ATP and NADPH in prostate cancer cells. 69 Clinically, p
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