For BRCA2 mutation carriers, we observed a decreasing trend in HR with increasing time since RRSO; relative to women who did not have an RSSO, the estimated HR > 5 years following RSSO was 0.51.
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Risk-reducing salpingo-oophorectomy, natural menopause, and breast cancer risk: an international prospective cohort of BRCA1 and BRCA2 mutation carriers.
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