Barely Significant
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Integrated targeted serum metabolomic profile and its association with gender, age, disease severity, and pattern identification in acne.

PLoS One · 2020 · PMC6968861 · PMID 31951642

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may not be significantno p-value reported
However, the systematic impact may not be significant, except in patients who develop many inflammatory lesions.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.