a nonsignificant trendp = 0.093
Post hoc comparisons revealed a significant reduction (43%) in mGluR5 binding in the hippocampus of AD ( BP ND = 0.76 ± 0.41) compared to CN ( BP ND = 1.34 ± 0.58, p = 0.003, unpaired t test) participants, and a nonsignificant trend for a reduction in a composite association cortical region in AD ( BP ND = 1.57 ± 0.25) compared to CN ( BP ND = 1.86 ± 0.63, p = 0.093) participants.