Interestingly, TNFRSF1A (encoding TNFR1) single nucleotide polymorphisms (SNPs) rs4149576 and rs4149577 were found to have highly significant genotypic associations with striatal but not hippocampal volume, whereas TNFRSF1B (encoding TNFR2) SNP rs1061624 yielded a significant association with hippocampal but not striatal volume [ 87 ].
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