Podoplanin Gene Disruption in Mice Promotes <i>in vivo</i> Neural Progenitor Cells Proliferation, Selectively Impairs Dentate Gyrus Synaptic Depression and Induces Anxiety-Like Behaviors.

In the in vitro experiments using neurospheres presented here, knockdown of Pdpn induced highly significant extensive cell death starting 4 days after cell differentiation ( Figure 4A ), indicating that Pdpn might be implicated in cell survival.

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