Activation of α7 nAChR by PNU-282987 improves synaptic and cognitive functions through restoring the expression of synaptic-associated proteins and the CaM-CaMKII-CREB signaling pathway.

Aging (Albany NY) · 2020 · PMC6977648 · PMID 31905173

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a decreasing trendno p-value reported

In the hippocampus of APP/PS1_DT mice, the CaM-CaMKII-CREB signaling pathway proteins demonstrated a decreasing trend, and this trend became more significant as the age of the mice increased.

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