Effect of Vitamin D on Blood Pressure and Hypertension in the General Population: An Update Meta-Analysis of Cohort Studies and Randomized Controlled Trials.

Similarly, the approximately L-shaped relationship between 25(OH)D levels and hypertension risk in our meta-analysis showed that hypertension risk increased substantially below 75 nmol/L but remained marginally significant above 75 nmol/L, which suggests that subjects with vitamin D insufficiency or deficiency show higher response to supplementation.

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